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KMID : 0360220120530050733
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Journal of the Korean Ophthalmological Society
2012 Volume.53 No. 5 p.733 ~ p.739
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Histopathologic Features of Triamcinolone Deposits in Refractory Steroid-Induced Glaucoma after Subtenon Triamcinolone Injection
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Jeon Hye-Shin
Park Won-Young
Lee Ji-Woong
Lee Ji-Eun
Oum Boo-Sup
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Abstract
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Purpose: To report the removal of subtenon triamcinolone precipitates in patients with refractory steroid-induced glaucoma following subtenon triamcinolone injection.
Case summary: A 72-year-old male patient with diabetic retinopathy had cystoid macular edema in the right eye. The patient received a posterior subtenon injection of triamcinolone acetonide and developed intractable glaucoma one month after the injection in the right eye. Corticosteroid-deposit was excised three month after the injection. The intraocular pressure decreased to normal within one month after surgery and remained normal for seven months after surgery. A
42-year-old man with bilateral chronic recurrent anterior uveitis received a posterior subtenon triamcinolone acetonide injection in both eyes. The patient developed refractory steroid-induced glaucoma one month after the injection in the right
eye. Corticosteroid-deposit was excised six months after the injection in the right eye. The patient’s intraocular pressure
decreased to normal within two weeks after surgery and remained normal. Light microscopy showed a fibrous capsule encapsulating an amorphous whitish material. The excised specimen with polarized light showed birefringence of triamcinolone crystals within an encapsulated cyst.
Conclusions: Removal of subtenon triamcinolone acetonide precipitate may facilitate the management of patients developing increased intraocular pressure unresponsive to maximum tolerable medical therapy and should be considered before performing glaucoma filtration surgery.
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KEYWORD
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Glaucoma, Subtenon, Triamcinolone
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